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Baba, Y., Inagaki, S., Nakagawa, S., Kaneko, T., Kobayashi, M., & Takihara, T. (2020). Effect of daily intake of green tea catechins on cognitive function in middle-aged and older subjects: A randomized, placebo-controlled study. Molecules, 25(18), 4265. https://doi.org/10.3390/molecules25184265.
Keywords: green tea, catechins, cognitive function, Cognitrax, middle-aged, randomized placebo-controlled trial.
Basu, T., Selman, A., Reddy, A. P., & Reddy, P. H. (2023). Current status of obesity: Protective role of catechins. Antioxidants, 12(2), 474. https://doi.org/10.3390/antiox12020474.
Keywords: obesity, mitochondrial dysfunction, hormonal deregulation, anti-inflammatory, antioxidant, catechins.
Bonuccelli, G., Sotgia, F., & Lisanti, M. P. (2018). Matcha green tea (MGT) inhibits the propagation of cancer stem cells (CSCs), by targeting mitochondrial metabolism, glycolysis and multiple cell signalling pathways. Aging, 10(8), 1867–1883. https://doi.org/10.18632/aging.101483.
Keywords: matcha green tea, cancer stem-like cells (CSCs), proteomics analysis, metabolism, mitochondrial OXPHOS, glycolysis.
Brown, E., Sadarangani, M., & Finlay, B. (2013). The role of the immune system in governing host-microbe interactions in the intestine. Nature Immunology, 14, 660–667. https://doi.org/10.1038/ni.2611.
Keywords: intestinal microbiota, commensal bacteria, innate immunity, adaptive immunity, immune regulation, inflammatory bowel disease (IBD), HIV, dysbiosis, pathogens, homeostasis, epithelial barrier, pattern recognition receptors (PRRs).
Dietz, C., Dekker, M., & Piqueras-Fiszman, B. (2017). An intervention study on the effect of matcha tea, in drink and snack bar formats, on mood and cognitive performance. Food research international (Ottawa, Ont.), 99(Pt 1), 72–83. https://doi.org/10.1016/j.foodres.2017.05.002.
Keywords: attention, caffeine, EGCG, matcha tea, memory, L-theanine.
Dulloo, A. G., Duret, C., Rohrer, D., Girardier, L., Mensi, N., Fathi, M., Chantre, P., & Vandermander, J. (1999). Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans. The American Journal of Clinical Nutrition, 70(6), 1040-1045. https://doi.org/10.1093/ajcn/70.6.1040.
Keywords: green tea extract, catechin, polyphenols, caffeine, energy expenditure, fat oxidation.
Eng, Q. Y., Thanikachalam, P. V., & Ramamurthy, S. (2018). Molecular understanding of Epigallocatechin gallate (EGCG) in cardiovascular and metabolic diseases. Journal of Ethnopharmacology, 210, 296–310. https://doi.org/10.1016/j.jep.2017.08.035.
Keywords: anti-inflammatory, antioxidant, atherosclerosis, diabetes, EGCG, heart failure.
Fahey, J. W., Stephenson, K. K., Dinkova-Kostova, A. T., Egner, P. A., Kensler, T. W., & Talalay, P. (2005). Chlorophyll, chlorophyllin and related tetrapyrroles are significant inducers of mammalian phase 2 cytoprotective genes. Carcinogenesis, 26, 1247–1255. https://doi.org/10.1093/carcin/bgi068.
Keywords: chlorophyll, oxidants, oxidation-reduction photosynthesis, mice liver cancer, metabolites rate.
Farhan, M. (2022). Green tea catechins: Nature’s way of preventing and treating cancer. International Journal of Molecular Sciences, 23(18), 10713. https://doi.org/10.3390/ijms231810713.
Keywords: EGCG, anticancer, cancer prevention, cancer therapy, green tea catechins.
Forester, S. C., & Lambert, J. D. (2011). The role of antioxidant versus pro-oxidant effects of green tea polyphenols in cancer prevention. Molecular Nutrition & Food Research, 55(6), 844–854. https://doi.org/10.1002/mnfr.201000641.
Keywords: camellia sinensis, (–)-epigallocatechin-3-gallate, green tea, antioxidant, cancer.
Fujiki, H., Suganuma, M., Okabe, S., Sueoka, E., Suga, K., Imai, K., Nakachi, K., & Kimura, S. (1999). Mechanistic findings of green tea as cancer preventive for humans. Proceedings of the Society for Experimental Biology and Medicine, 220(4), 225–228. https://doi.org/10.1046/j.1525-1373.1999.d01-38.x.
Keywords: green tea, EGCG, cancer prevention, mechanisms of action, antitumor effects.
Hidese, S., Ogawa, S., Ota, M., Ishida, I., Yasukawa, Z., Ozeki, M., & Kunugi, H. (2019). Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial. Nutrients, 11(10), 2362. https://doi.org/10.3390/nu11102362.
Keywords: cognition, emotion, L-theanine, sleep, stress.
Hursel, R., Viechtbauer, W., & Westerterp-Plantenga, M. S. (2009). The effects of green tea on weight loss and weight maintenance: A meta-analysis. International Journal of Obesity, 33(9), 956–961. https://doi.org/10.1038/ijo.2009.135.
Keywords: green tea, weight loss, weight maintenance, catechins, caffeine intake.
ITO EN, Ltd., & MCBI Inc. (2022, August 2). Daily Intake of Matcha Confirmed to Improve Sleep Quality and Social Cognitive Function, Presented at Alzheimer’s Association International Conference (AAIC2022).
Keywords: matcha, sleep quality, cognitive function.
Kapoor, M. P., Sugita, M., Fukuzawa, Y., & Okubo, T. (2017). Physiological effects of epigallocatechin-3-gallate (EGCG) on energy expenditure for prospective fat oxidation in humans: A systematic review and meta-analysis. The Journal of Nutritional Biochemistry, 43, 1–10. https://doi.org/10.1016/j.jnutbio.2016.10.013.
Keywords: catechins, energy expenditure, epigallocatechin-3-gallate, fat oxidation, respiratory quotient.
Kim, J. H., Kim, J. W., Kim, C. Y., Jeong, J. S., Ko, J. W., & Kim, T. W. (2023). Green tea extract ameliorates macrophage-driven emphysematous lesions in chronic obstructive pulmonary disease induced by cigarette smoke condensate. Phytotherapy research : PTR, 37(4), 1366–1376. https://doi.org/10.1002/ptr.7745.
Keywords: chronic obstructive pulmonary disease, cigarette smoke, emphysema, green tea extract, macrophage, protease/antiprotease imbalance.
Kochman, J., Jakubczyk, K., Antoniewicz, J., Mruk, H., & Janda, K. (2020). Health Benefits and Chemical Composition of Matcha Green Tea: A Review. Molecules (Basel, Switzerland), 26(1), 85. https://doi.org/10.3390/molecules26010085.
Keywords: matcha, green tea, catechins, EGCG, Camellia sinensis, chemical composition, health-promoting effect, polyphenols.
Koláčková, T., Kolofiková, K., Sytařová, I., Snopek, L., Sumczynski, D., & Orsavová, J. (2020). Matcha Tea: Analysis of Nutritional Composition, Phenolics and Antioxidant Activity. Plant foods for human nutrition (Dordrecht, Netherlands), 75(1), 48–53. https://doi.org/10.1007/s11130-019-00777-z.
Keywords: antioxidant activity, HPLC, matcha tea, nutritional composition, phenolics.
Kopec, R. E. (2022, March). Chlorophyll and metallo-chlorophyll derivatives. Linus Pauling Institute. Retrieved April 30, 2024, from https://lpi.oregonstate.edu/mic/dietary-factors/phytochemicals/chlorophyll-metallo-chlorophyll-derivatives. Original author: Jane Higdon, Ph.D. (2004); Updated by Jane Higdon, Ph.D. (2005), Victoria J. Drake, Ph.D. (2009, 2021); Reviewed by Rachel E. Kopec, Ph.D. (2022).
Keywords: chlorophyll.
Ku, K. M., Choi, J. N., Kim, J., Kim, J. K., Yoo, L. G., Lee, S. J., Hong, Y. S., & Lee, C. H. (2010). Metabolomics analysis reveals the compositional differences of shade grown tea (Camellia sinensis L.). Journal of agricultural and food chemistry, 58(1), 418–426. https://doi.org/10.1021/jf902929h.
Keywords: green tea, tencha, antioxidant, shading culture, multivariate analysis, metabolomics.
Kurauchi, Y., Devkota, H. P., Hori, K., Nishihara, Y., Hisatsune, A., Seki, T., Katsuki, H. (2019). Anxiolytic activities of Matcha tea powder, extracts, and fractions in mice: Contribution of dopamine D1 receptor- and serotonin 5-HT1A receptor-mediated mechanisms. Journal of Functional Foods, 59, 301-308. https://doi.org/10.1016/j.jff.2019.05.046.
Keywords: matcha, dopamine, serotonin.
Kurauchi, Y., Ohta, Y., Matsuda, K., Sanematsu, W., Devkota, H. P., Seki, T., & Katsuki, H. (2023). Matcha tea powder’s antidepressant-like effect through the activation of the dopaminergic system in mice is dependent on social isolation stress. Nutrients, 15(3), 581. https://doi.org/10.3390/nu15030581.
Keywords: depression, dopaminergic circuit, matcha.
Li, M. Y., Liu, H. Y., Wu, D. T., Kenaan, A., Geng, F., Li, H. B., Gunaratne, A., Li, H., & Gan, R. Y. (2022). L-Theanine: A unique functional amino acid in tea (Camellia sinensis L.) with multiple health benefits and food applications. Frontiers in Nutrition, 9, 853846. https://doi.org/10.3389/fnut.2022.853846.
Keywords: L-theanine, tea, health benefits, mechanisms of action, food applications.
Li, X. X., Liu, C., Dong, S. L., Ou, C. S., Lu, J. L., Ye, J. H., Liang, Y. R., & Zheng, X. Q. (2022). Anticarcinogenic potentials of tea catechins. Frontiers in Nutrition, 9, 1060783. https://doi.org/10.3389/fnut.2022.1060783.
Keywords: Camellia sinensis, tea catechins, anticancer, antioxidant, free radicals, synergistic interaction, metastasis, signaling pathway.
Lopes Sakamoto, F., Metzker Pereira Ribeiro, R., Amador Bueno, A., & Oliveira Santos, H. (2019). Psychotropic effects of L-theanine and its clinical properties: From the management of anxiety and stress to a potential use in schizophrenia. Pharmacological Research, 147, 104395. https://doi.org/10.1016/j.phrs.2019.104395.
Keywords: (L)-theanine, anxiety, camellia sinensis, green tea, psychological stress, schizophrenia.
Madigan, M., & Karhu, E. (2018). The role of plant-based nutrition in cancer prevention. Journal of Unexplored Medical Data, 3, 9. http://dx.doi.org/10.20517/2572-8180.2018.05.
Keywords: vegan nutrition, plant-based diet, cancer, nutritional therapy.
Martins, T., Barros, A. N., Rosa, E., & Antunes, L. (2023). Enhancing Health Benefits through Chlorophylls and Chlorophyll-Rich Agro-Food: A Comprehensive Review. Molecules (Basel, Switzerland), 28(14), 5344. https://doi.org/10.3390/molecules28145344.
Keywords: chlorophylls, chlorophyllin, health, biological activity.
Miura, Y., Chiba, T., Tomita, I., Koizumi, H., Miura, S., Umegaki, K., Hara, Y., & Ikeda, M. (2001). Tea Catechins Prevent the Development of Atherosclerosis in Apoprotein E–Deficient Mice. Journal of Nutrition, 131, 27–32. https://doi.org/10.1093/jn/131.1.27.
Keywords: apoprotein E–deficient mice, atherosclerosis, catechins, antioxidants, aortic lipids.
Nagao, T., Komine, Y., Soga, S., Meguro, S., Hase, T., Tanaka, Y., & Tokimitsu, I. (2005). Ingestion of a tea rich in catechins leads to a reduction in body fat and malondialdehyde-modified LDL in men. The American Journal of Clinical Nutrition, 81(1), 122–129. https://doi.org/10.1093/ajcn/81.1.122.
Keywords: green tea extract, catechins, humans, body fat, malondialdehyde-modified LDL, double-blind controlled study.
Ng, T. P., Gao, Q., Gwee, X., Chua, D. Q. L., & Tan, W. C. (2021). Tea Consumption and Risk of Chronic Obstructive Pulmonary Disease in Middle-Aged and Older Singaporean Adults. International journal of chronic obstructive pulmonary disease, 16, 13–23. https://doi.org/10.2147/COPD.S273406.
Keywords: phytochemical, polyphenols, theophylline, epidemiological, longitudinal.
Nobre, A. C., Rao, A., & Owen, G. N. (2008). L-theanine, a natural constituent in tea, and its effect on mental state. Asia Pacific journal of clinical nutrition, 17 Suppl 1, 167–168.
Keywords: L-theanine, brain function, alpha activity, mental alertness, arousal, dietary levels.
Oh, C. M., Oh, I. H., Choe, B. K., Yoon, T. Y., Choi, J. M., & Hwang, J. (2018). Consuming Green Tea at Least Twice Each Day Is Associated with Reduced Odds of Chronic Obstructive Lung Disease in Middle-Aged and Older Korean Adults. The Journal of nutrition, 148(1), 70–76. https://doi.org/10.1093/jn/nxx016.
Keywords: chronic obstructive lung disease, forced expiratory volume, forced vital capacity, green tea, lung function.
Oh, J. W., Muthu, M., Pushparaj, S. S. C., & Gopal, J. (2023). Anticancer therapeutic effects of green tea catechins (GTCs) when integrated with antioxidant natural components. Molecules, 28(5), 2151. https://doi.org/10.3390/molecules28052151.
Keywords: green tea catechins, antioxidant, natural compounds, anticancer, mechanisms, apoptosis.
Pae, M., & Wu, D. (2013). Immunomodulating effects of epigallocatechin-3-gallate from green tea: Mechanisms and applications. Food & Function, 4(9), 1287–1303. https://doi.org/10.1039/c3fo60076a.
Keywords: EGCG, green tea, immunomodulation, T cells, autoimmune diseases.
Park, J. H., Bae, J. H., Im, S. S., & Song, D. K. (2014). Green tea and type 2 diabetes. Integrative Medicine Research, 3(1), 4-10. https://doi.org/10.1016/j.imr.2013.12.002.
Keywords: catechins, glucose uptake, green tea, obesity, type 2 diabetes.
Pérez-Burillo, S., Navajas-Porras, B., López-Maldonado, A., Hinojosa-Nogueira, D., Pastoriza, S., & Rufián-Henares, J. Á. (2021). Green Tea and Its Relation to Human Gut Microbiome. Molecules, 26(13), 3907. https://doi.org/10.3390/molecules26133907.
Keywords: green tea, gut microbiota, catechin, polyphenols, health.
Pervin, M., Unno, K., Takagaki, A., Isemura, M., & Nakamura, Y. (2019). Function of green tea catechins in the brain: Epigallocatechin gallate and its metabolites. International Journal of Molecular Sciences, 20(15), 3630. https://doi.org/10.3390/ijms20153630.
Keywords: blood–brain barrier, catechin, cognition, epigallocatechin gallate, green tea, microbiota.
Pham-Huy, L. A., He, H., & Pham-Huy, C. (2008). Free Radicals, Antioxidants in Disease and Health. International Journal of Biomedical Science, 4(2), 89-96.
Keywords: antioxidants, beneficial effects, deleterious effects, diseases, free radicals, health, oxidative stress.
Phuah, Y. Q., Chang, S. K., Ng, W. J., Lam, M. Q., & Ee, K. Y. (2023). A review on matcha: Chemical composition, health benefits, with insights on its quality control by applying chemometrics and multi-omics. Food Research International, 170, 113007. https://doi.org/10.1016/j.foodres.2023.113007.
Keywords: matcha, processing, chemical composition, health benefits, quality, chemometrics, multi-omics.
Rawangkan, A., Wongsirisin, P., Namiki, K., Iida, K., Kobayashi, Y., Shimizu, Y., Fujiki, H., & Suganuma, M. (2018). Green tea catechin is an alternative immune checkpoint inhibitor that inhibits PD-L1 expression and lung tumor growth. Molecules, 23(8), 2071. https://doi.org/10.3390/molecules23082071.
Keywords: (−)-epigallocatechin gallate, immune checkpoint, interferon-γ, epidermal growth factor, lung tumor.
Saito, E., Inoue, M., Sawada, N., Shimazu, T., Yamaji, T., Iwasaki, M., Sasazuki, S., Noda, M., Iso, H., Tsugane, S., Hanaoka, T., Ogata, J., Baba, S., Mannami, T., Okayama, A., Kokubo, Y., Miyakawa, K., Saito, F., Koizumi, A., Sano, Y., … Akiba, S. (2015). Association of green tea consumption with mortality due to all causes and major causes of death in a Japanese population: the Japan Public Health Center-based Prospective Study (JPHC Study). Annals of Epidemiology, 25(7), 512-518.e3. https://doi.org/10.1016/j.annepidem.2015.03.007.
Keywords: prospective cohort study, Japanese adults, green tea intake, all-cause mortality, heart disease mortality, cerebrovascular disease mortality, respiratory disease mortality, cancer mortality, injury, dose-response, caffeine intake, polyphenols, cardiovascular mechanisms, respiratory mechanisms.
Sakurai, K., Shen, C., Ezaki, Y., Inamura, N., Fukushima, Y., Masuoka, N., & Hisatsune, T. (2020). Effects of Matcha Green Tea Powder on Cognitive Functions of Community-Dwelling Elderly Individuals. Nutrients, 12(12), 3639. https://doi.org/10.3390/nu12123639.
Keywords: green tea, cognitive function, memory function, impulsivity, aging, vitamin K.
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Keywords: caffeine, health benefits, athletic effects, dietary supplements, nanocarriers.
Sharangi, A. B. (2009). Medicinal and Therapeutic Potentialities of Tea (Camellia Sinensis L.) —A Review. Food Research International, 42, 529–535. https://doi.org/10.1016/j.foodres.2009.01.007.
Keywords: tea, camellia sinensis, medicinal and therapeutic values, ethno medicine, human health.
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Keywords: cancer, cardiovascular disease, catechin, chemoprevention, green tea, metabolic syndrome, neurodegenerative disease, obesity.
Sheng, Y., Sun, Y., Tang, Y., Yu, Y., Wang, J., Zheng, F., Li, Y., & Sun, Y. (2023). Catechins: Protective mechanism of antioxidant stress in atherosclerosis. Frontiers in Pharmacology, 14, 1144878. https://doi.org/10.3389/fphar.2023.1144878.
Keywords: catechins, oxidative stress, atherosclerosis, lipid metabolism disorders, tea.
Sokary, S., Al-Asmakh, M., Zakaria, Z., & Bawadi, H. (2022). The therapeutic potential of matcha tea: A critical review on human and animal studies. Current research in food science, 6, 100396. https://doi.org/10.1016/j.crfs.2022.11.015.
Keywords: matcha tea, catechins, cognitive function, cardio-metabolic, Anti-tumor.
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Keywords: adrenal hypertrophy, anxiety, caffeine, catechin, green tea, matcha, salivary α-amylase activity, stress-reduction, theanine.
Vázquez-Durán, A., Téllez-Isaías, G., Hernández-Rodríguez, M., Ruvalcaba, R. M., Martínez, J., Nicolás-Vázquez, M. I., Aceves-Hernández, J. M., & Méndez-Albores, A. (2022). The Ability of Chlorophyll to Trap Carcinogen Aflatoxin B1: A Theoretical Approach. International Journal of Molecular Sciences, 23, 6068. https://doi.org/10.3390/ijms23116068.
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Wang, Y., Yu, Y., Ding, L., Xu, P., & Zhou, J. (2022). Matcha green tea targets the gut-liver axis to alleviate obesity and metabolic disorders induced by a high-fat diet. Frontiers in nutrition, 9, 931060. https://doi.org/10.3389/fnut.2022.931060.
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Keywords: epigallocatechin-3-gallate (EGCG), ascorbic acid, liver cancer, cell proliferation, cell migration.
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Keywords: catechins, green tea, matcha, micellar electrokinetic chromatography, epigallocatechin gallate (EGCG).
Wen, L., Wu, D., Tan, X., Zhong, M., Xing, J., Li, W., Li, D., & Cao, F. (2022). The Role of Catechins in Regulating Diabetes: An Update Review. Nutrients, 14(21), 4681. https://doi.org/10.3390/nu14214681.
Keywords: tea, hyperglycemia, insulin resistance, oxidative stress, mitochondrial damage, gut.
Westerterp-Plantenga, M. S., Lejeune, M. P. G. M., & Kovacs, E. M. R. (2005). Body weight loss and weight maintenance in relation to habitual caffeine intake and green tea supplementation. Obesity Research, 13, 1195-1204. https://doi.org/10.1038/oby.2005.142
Keywords: clinical trial, green tea supplementation, habitual caffeine intake, body weight loss, weight maintenance.
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Keywords: matcha, antioxidant status, lipid levels, glucose levels, serum total cholesterol (TC), triglyceride (TG) levels, high-density lipoprotein-cholesterol (HDL-C), low-density lipoprotein-cholesterol (LDL-C), blood glucose levels, superoxide dismutase (SOD), malondialdehyde (MAD), Serum GSH-Px activity, oxidative stress.
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Keywords: L-theanine, serum amino acids profiles, nutrients absorption, intestinal gene expression, glucose uptake, insulin secretion, amino acid transporters, glucose transporters, fatty acid transporters, G-protein-coupled receptors, green tea.
Yang, C. S., & Wang, H. (2016). Cancer preventive activities of tea catechins. Molecules, 21(12), 1679. https://doi.org/10.3390/molecules21121679.
Keywords: tea catechins, EGCG, cancer signaling, animal models, cell lines.
Yang, C. S., Zhang, J., Zhang, L., Huang, J., & Wang, Y. (2016). Mechanisms of body weight reduction and metabolic syndrome alleviation by tea. Molecular Nutrition & Food Research, 60(1), 160–174. https://doi.org/10.1002/mnfr.201500428.
Keywords: AMPK, diabetes, EGCG, obesity, tea.
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Keywords: caffeine, L-Theanine, cognitive performance, curling.
Zheng, H., You, Y., Hua, M., Wu, P., Liu, Y., Chen, Z., Zhang, L., Wei, H., Li, Y., Luo, M., Zeng, Y., Liu, Y., Luo, D. X., Zhang, J., Feng, M., Hu, R., Pandol, S. J., & Han, Y. P. (2018). Chlorophyllin Modulates Gut Microbiota and Inhibits Intestinal Inflammation to Ameliorate Hepatic Fibrosis in Mice. Frontiers in Physiology, 9, 1671. https://doi.org/10.3389/fphys.2018.01671.
Keywords: sodium copper chlorophyllin, liver fibrosis, intestinal tissue barrier, gut microbiota dysbiosis, NF-κB pathway.
Zhou, J., Yu, Y., Ding, L., Xu, P., & Wang, Y. (2021). Matcha Green Tea Alleviates Non-Alcoholic Fatty Liver Disease in High-Fat Diet-Induced Obese Mice by Regulating Lipid Metabolism and Inflammatory Responses. Nutrients, 13(6), 1950. https://doi.org/10.3390/nu13061950.
Keywords: matcha green tea, nonalcoholic fatty liver disease, nonalcoholic steatohepatitis, fatty toxicity, lipid droplets-associated proteins, cytochrome P450.
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